OVERVIEW OF OXYGEN SATURATION IN COVID-19 PATIENTS AT RUANG ISOLASI RSU NEGARA
Abstract
Introduction. Coronavirus Disease 2019 (COVID-19) is a contagious respiratory system infection caused by a new type of Coronavirus. COVID-19 infection can cause mild, moderate, or severe symptoms in the form of fever, tachypnea, severe respiratory distress, and hypoxemia. Oxygen saturation is an indicator of oxygenation status. Hypoxemia is an important prognostic indicator of hospital length of stay and death. Objectives. To determine the description of oxygen saturation in COVID-19 patients during treatment in the Ruang Isolasi RSU Negara. Methods. Descriptive study with a retrospective approach, to examine the medical records of COVID-19 patients with moderate and severe symptoms. Results. The number of COVID-19 patients treated in Ruang Isolasi RSU Negara during the 2020-2022 study was 384 patients. Most of them had moderate symptoms (70.05%). SpO2 values <93% were found more frequently in men (51.11%) and in the age group 41-60 years (49.63%). Comorbid DM was more commonly found at SpO2 values <93% (23.02%) and pneumonia was more common at SpO2 values <93% (97.21%). Conclusions. Patients with SpO2 values <93% were more likely to be male patients, age group 41-60 years, with comorbid DM and pneumonia. Women's immune systems are superior to men's due to hormonal protection. Hypertension and diabetes mellitus are low-grade inflammation (systemic inflammatory processes) and cause more severe organ damage. An increase in pro-inflammatory cytokines in serum is associated with inflammation in the lungs, causing pneumonia.
Downloads
References
Burhan, E., Susanto, A. D., Nasution, S. A., Ginanjar, E., Pitoyo, C. W., Susilo, A., Firdaus, I., Santoso, A., Juzar, D. A., Arif, S. K., Wulung, N. G. H. L., Adityaningsih, D., Syam, A. F., Rasmin, M., Rengganis, I., Sukrisman, L., Damayanti, T., Wiyono, W. H., Prasenohadi, … Dharmawan, I. (2022). Pedoman Tatalaksana COVID-19 (4th ed.). PAPDI, PERKI, PAPDI, PERDATIN, IDAI.
Busana, M., Gasparetti, A., Giosa, L., Forleo, G. B., Schiavone, M., Mitacchione, G., Bonino, C., Villa, P., Galli, M., Tondo, C., Saguner, A., Steiger, P., Curnis, A., Dellorusso, A., Pugliese, F., Mancone, M., Marini, J. J., & Gattinoni, L. (2021). Prevalence and outcome of silent hypoxemia in COVID-19. Minerva Anestesiologica, 87(3), 325–333. https://doi.org/10.23736/S0375-9393.21.15245-9
Chang, W.H. (2020). Understanding the COVID-19 pandemic from a gender perspective. Taiwan J Obstet Gynecol, 59(6):801–7. https://doi.org/10.1016/j.tjog.2020.09.004
Fatoni, A. Z., & Rakhmatullah, R. (2021). Acute Respiratory Distress Syndrome (ARDS) pada Pneumonia COVID-19. Journal of Anaesthesia and Pain, 2(1), 11–24. http://dx.doi.org/10.21776/ub.jap.2021.002.01.02
Karya, K.W.S., Suwidnya, M., & Wijaya, B.S. (2021). Hubungan penyakit komorbiditas terhadap derajat klinis COVID-19. Intisari Sains Medis, 12(2), 708-717. https://doi.org/10.15562/ism.v12i2.1143
Lim, S., Bae, J.H., Kwon, H.S., & Nauck, M.A. (2021). COVID-19 and diabetes mellitus: from pathophysiology to clinical management. Nature Reviews Endocrinology, 17, 11-30. https://doi.org/10.1038/s41574-020-00435-4
Parasher, A. (2021). COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment. Postgraduate Medical Journal, 97(1147), 312–320. https://doi.org/10.1136/postgradmedj-2020-138577
Putra, M.A.A. & Fenty. (2022). Hubungan komorbiditas terhadap derajat keparahan admisi dan outcome pasien COVID-19. Journal of Health Promotion and Service Management, 1(1), 11-18. https://doi.org/10.52232/jhpsm.v1i1.57
Radwan, N.M., Mahmoud, N.E., Alfaifi, A.H., & Alabdulkareem, K.I. (2020). Comorbidities and severity of coronavirus disease 2019 patients. Saudi Med J., 41(11):1165–74. https://doi.org/10.15537/smj.2020.11.25454
Swenson, K. E., & Hardin, C. C. (2023). Pathophysiology of Hypoxemia in COVID-19 Lung Disease. Clinics in Chest Medicine, 44(2), 239–248. https://doi.org/10.1016/j.ccm.2022.11.007
Tompodung, C.O., Sapulete, I.M., & Pangemanan, D.H. (2022). Gambaran Saturasi Oksigen dan Kadar Hemoglobin pada Pasien COVID-19. eBiomedik, 10(1), 35-41. https://doi.org/10.35790/ebm.v10i1.37996
Copyright (c) 2024 Luh Putu Santini
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.